Egg freezing poses health risks to women

07/21/2015 11:00

by Marcy Darnovsky


The decision by Facebook and Apple to offer their female employees a $20,000 benefit to freeze their eggs for later use with in vitro fertilization is ill-advised for numerous reasons, says the Center for Genetics and Society (CGS). These include the significant but under-studied risks of egg retrieval for women, and the dearth of evidence about potential long-term health risks to children born as a result of the egg-freezing process.


The firestorm of critical response to the companies' new policy has focused on important concerns including the high failure rates of IVF, the pressure to defer childbearing that the policy represents, and Silicon Valley companies' lack of attention to family-friendly workplace policies, including paid leave and schedule flexibility that would enable work-family balance.


So far, however, there has been little focus on a critical concern:  egg retrieval poses serious health risks to women. Getting your eggs frozen is neither a simple nor a safe procedure, said Marcy Darnovsky, PhD, executive director of CGS. Retrieving multiple eggs involves injections of powerful hormones, some of them used off-label and never approved for egg extraction. The short-term risks range from mild to very severe, and the long-term risks are uncertain because they haven't been adequately studied  even though the fertility industry has been using these hormones for decades


The hormonal drugs used to hyper-stimulate ovary production can cause what is known as ovarian hyperstimulation syndrome (OHSS) in the short term. Mild cases of OHSS are characterized by nausea, bloating, and discomfort. Serious cases are relatively infrequent but can require hospitalization for complications including intra-abdominal bleeding, ovarian torsion, and severe pain. Deaths, fortunately rare, have been reported


The severity and frequency of long-term risks, including infertility and cancer, are not well established because of inadequate follow-up studies of women who have undergone egg retrieval. The risks to children born from frozen eggs are also under-studied, although the chemicals used in the freezing process are known to be toxic.


Furthermore, encouraging egg freezing may commit more women to undergoing IVF, which has been linked to an increase in stillbirths, cesarean sections, preterm deliveries, multiple gestations, and higher rates of fetal anomalies.


Both the American College of Obstetricians and Gynecologists and the American Society for Reproductive Medicine have issued guidelines explicitly discouraging women from utilizing egg freezing for elective, non-medical reasons.


Why are Facebook and Apple endorsing a technique that encourages their employees to put their health at risk?, Darnovsky asked. Paying for egg freezing is being presented as a benefit for women, but it may be that discouraging women from balancing work and family is really a benefit to the companies



The Center for Genetics and Society (CGS) is a non-profit public affairs and policy advocacy organization working to encourage responsible uses and effective societal governance of human genetic and reproductive biotechnologies. The article first appeared here.

[Note:  See also: Frozen II:  The Tech Industry's Eggs, by Marcy Darnovsky, The Weekly Wonk:  A group of experts react to the news that Apple and Facebook will pay for female employees to freeze their eggs;  at:


Another Reason Freezing Employees' Eggs is a Terrible Idea, by Ricki Lewis, PLOS Blogs:  Facebook and Apple's decision to offer female employees a $20,000 benefit to freeze their eggs indicates a stunning disregard for the complexities of reproductive biology;  at:


Freezing Eggs Puts Women and Infants' Health at Stake, by Miriam Zoll, The New York Times:  Responsible doctors should not be recommending egg freezing to perfectly healthy younng women who have no medically indicated need;  at:


Left Out in The Cold:  Seven Reasons Not To Freeze Your Eggs, by Francoise Baylis, Impact Ethics:  Apparently the professional cautions against egg freezing from the American Society for Reproductive Medicine are of no consequence to Facebook or Apple;  at:

--  DNI]